Adaptive Regulation of Organ Size (AROS) Lab
Timeline of the lab
- June 2018: The AROS lab is founded at the Australian Regenerative Medicine Institute (Monash Univ., Melbourne).
- June 2023: A new branch of the AROS lab is started at the University of Cambridge (UK). Alberto starts travelling back and forth between both locations, becoming (almost) immune to jet lag.
Regulation of Gli1+ chondroprogenitors upon perturbation of cartilage growth in the developing limbs (PhD, postdoc) Combining lineage-specific gene overexpression with lineage tracing, single-cell genomics and mathematical modelling, we will unravel the feedback mechanisms that control the number and behaviour of the Gli1+ cartilage progenitors that drive bone growth in the limb. Contact us
Role of mechanotransduction in the control of final bone size (Master, PhD)
We have recently become interested in how mechanical cues influence organ development and regeneration. Combining microsurgeries in chicken-embryo limbs with imaging of tension reporters and spatial transcriptomic, we will explore how mechanical tension in certain tissues modulate growth of the long bones. Contact us